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pentobarbital will lower the extent or outcome of atazanavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unknown.pentobarbital increases effects of ifosfamide by affecting hepatic enzyme CYP2B6 metabolism. Use Warning/Keep track of. Coadministration of ifosfamide with CYP2B6 inducers might boost metabolism of ifosfa